Fusion event
HBV-DLG1 integration
Detection method
invPCR +Sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Integrated sequence
GAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGA| |TGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGG
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7g/Upstream/1194360; hsa-mir-4797/Downstream/217123;
Nearest cancer related gene
Upstream sequence
GTACAAAGGCCCAGCCTAGCA
Junction sequence
GTACAAAGGCCCAGCCTAGCAGCATGGTGCTGGTGAACAGA
* Color:
Human Sequence
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Virus Sequence
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Overlapped sequence
/
Unknown sequence
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.