Basic Information
VIS ID
TVIS10006428
Fusion event
HBV-LOC285500 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1820
Integrated sequence
AGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGAT| |GTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGA
Host Sequence
Chromosome
chr4
Cytoband
q34.3
Reference genome
GRCh38
Start
177597656 (Hg38)
End
177597656 (Hg38)
Location type
Intronic
Target gene
LOC285500
Nearest miRNA
hsa-mir-12113/Upstream/3173792; hsa-mir-1305/Downstream/4571637;
Nearest TSS
ENST00000502981/Upstream/152677; ENST00000507870/Downstream/93412;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/155102, chr4-CpG: 160/Downstream/2460229
Nearby gene
AGA(-155153) ; LINC01098(+131100) ;
Upstream sequence
ACTTAGAAGCTTTACCTC
Junction sequence
ACTTAGAAGCTTTACCTCTGCATGGTGCTGGTGAACA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate