Basic Information
VIS ID
TVIS10006437
Fusion event
HBV-LINC01788 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1803
Integrated sequence
AGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTA| |GCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAG
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh38
Start
70708693 (Hg38)
End
70708693 (Hg38)
Location type
Intron
Fragile sites / regions
FRA1L
Target gene
LINC01788
Nearest miRNA
hsa-mir-101-1/Upstream/2525083; hsa-mir-11399/Downstream/358938;
Nearest TSS
ENST00000473358/Upstream/2240; ENST00000426775/Downstream/11596;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/297285, chr1-CpG: 131/Downstream/337848
Upstream sequence
GTCAGACAAGTAATGACTG
Junction sequence
GTCAGACAAGTAATGACTGnnnnnnnnCAGACCAATTTATGCCTACA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate