Basic Information
VIS ID
TVIS10006438
Fusion event
HBV-LOC105371240 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1798
Integrated sequence
GAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACA| |GCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCG
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh38
Start
48633860 (Hg38)
End
48633860 (Hg38)
Location type
Intronic
Target gene
LOC105371240
Nearest miRNA
hsa-mir-1225/Upstream/14470187; hsa-mir-11401/Downstream/1658756;
Nearest TSS
ENST00000527434/Upstream/10398; ENST00000561876/Downstream/3283;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/136962, chr16-CpG: 87/Downstream/176780
Nearby gene
N4BP1(-23651) ; CBLN1(+645543) ;
Downstream sequence
TGGGTCCAGACCACTTAAG
Junction sequence
GAGGCTGTAGGCATAAATTGTGGGTCCAGACCACTTAAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate