Basic Information
VIS ID
TVIS10006440
Fusion event
HBV-chr1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1826
Integrated sequence
GTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATAT| |TTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCA
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
GRCh38
Start
38590990 (Hg38)
End
38590990 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-12136/Upstream/501661; hsa-mir-101-1/Downstream/2163365;
Nearest TSS
ENST00000473358/Upstream/115794; ENST00000456813/Downstream/183518;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/12129, chr1-CpG: 45/Downstream/117717
Nearby gene
LINC01343(-367223) ; RRAGC(+260624) ;
Upstream sequence
AAAAGAAAAAAATTAACTTAG
Junction sequence
AAAAGAAAAAAATTAACTTAGAAAAGTTGCATGGTGCTGGT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate