VISDB Viral Integration Site DataBase

VIS ID

TVIS10006442

Fusion event

HBV-PAX5 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1799

Integrated sequence

AGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAG| |CCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGG

Chromosome

chr9

Cytoband

p13.2

Reference genome

Start

End

36836065 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-6834-5p ; hsa-mir-4710 ; hsa-mir-7106-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-6875-5p ; hsa-mir-4419a ; hsa-mir-3126-5p ; hsa-mir-6730-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-6890-5p ; hsa-mir-3675-5p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-7109-3p ; hsa-mir-1321 ; hsa-mir-548m ; hsa-mir-767-5p ; hsa-mir-3130-3p ; hsa-mir-3714 ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-4666a-5p ; hsa-mir-6867-5p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-4531 ; hsa-mir-3653-3p ; hsa-mir-139-3p ; hsa-mir-153-5p

Nearest miRNA

hsa-mir-101-2/Upstream/12466; hsa-let-7a-1/Downstream/28189;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/96280, chr9-CpG: 20/Downstream/45888

Nearest cancer related gene

PAX5(TSG, No orient, 0)

Downstream sequence

CTGCCAAGGCTGGGCAGTCGTT

Junction sequence