VISDB Viral Integration Site DataBase

VIS ID

TVIS10006445

Fusion event

HBV-MAP2K7 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1825

Integrated sequence

GGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATA| |TTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGC

Chromosome

chr19

Cytoband

p13.2

Reference genome

Start

End

7905028 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-125a-5p ; hsa-mir-493-3p ; hsa-mir-218-5p ; hsa-mir-4732-5p ; hsa-mir-4451 ; hsa-mir-6722-3p ; hsa-mir-6077 ; hsa-mir-1909-3p ; hsa-mir-98-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-3928-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-6510-5p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-2278 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-8080 ; hsa-mir-4311 ; hsa-mir-125b-1-3p ; hsa-mir-1182 ; hsa-mir-1207-5p ; hsa-mir-1321 ; hsa-mir-138-5p ; hsa-mir-149-3p ; hsa-mir-1827 ; hsa-mir-1972 ; hsa-mir-198 ; hsa-mir-24-3p ; hsa-mir-3155a ; hsa-mir-3155b ; hsa-mir-3178 ; hsa-mir-3652 ; hsa-mir-3934-3p ; hsa-mir-4270 ; hsa-mir-4299 ; hsa-mir-4430 ; hsa-mir-4441 ; hsa-mir-4505 ; hsa-mir-4524a-3p ; hsa-mir-4650-5p ; hsa-mir-4711-5p ; hsa-mir-4723-5p ; hsa-mir-4728-5p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-4763-3p ; hsa-mir-484 ; hsa-mir-5197-3p ; hsa-mir-520a-5p ; hsa-mir-525-5p ; hsa-mir-5698 ; hsa-mir-5787 ; hsa-mir-635 ; hsa-mir-6499-5p ; hsa-mir-6731-5p ; hsa-mir-6746-5p ; hsa-mir-6754-5p ; hsa-mir-6757-5p ; hsa-mir-6774-5p ; hsa-mir-6785-5p ; hsa-mir-6795-5p ; hsa-mir-6799-5p ; hsa-mir-6804-5p ; hsa-mir-6808-5p ; hsa-mir-6825-5p ; hsa-mir-6842-3p ; hsa-mir-6853-5p ; hsa-mir-6870-5p ; hsa-mir-6873-5p ; hsa-mir-6883-5p ; hsa-mir-6887-5p ; hsa-mir-6893-5p ; hsa-mir-7111-5p ; hsa-mir-7152-3p ; hsa-mir-8085 ; hsa-mir-889-5p ; hsa-mir-940

Nearest miRNA

hsa-mir-1227/Upstream/287523; hsa-let-7e/Downstream/484262;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/492, chr19-CpG: 24/Downstream/7558

Upstream sequence

GTACCTCTCGCTTCACACACAC

Junction sequence