GRM7 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006446
Fusion event
HBV-GRM7 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1822
Integrated sequence
AAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGT| |ATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATC
Host Sequence
Chromosome
chr3
Cytoband
p26.1
Reference genome
GRCh38
Start
7363687 (Hg38)
End
7363687 (Hg38)
Location type
Intron
Target gene
GRM7
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-34c-5p
Nearest miRNA
hsa-mir-4790/Upstream/2113432; hsa-let-7g/Downstream/2916664;
Nearest TSS
ENST00000440867/Upstream/65004; ENST00000445087/Downstream/39363;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/500733, chr3-CpG: 42/Downstream/1137828
Upstream sequence
GGTCTCATCCAAT
Junction sequence
GGTCTCATCCAATGTTGCATGGTGCTGGTGAAC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate