VISDB Viral Integration Site DataBase

VIS ID

TVIS10006447

Fusion event

HBV-STS integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1828

Integrated sequence

CGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTT| |GCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGA

Chromosome

chrX

Cytoband

p22.31

Reference genome

Start

End

7273398 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-148b-3p ; hsa-mir-4662a-5p ; hsa-mir-539-5p ; hsa-mir-3651 ; hsa-mir-3976 ; hsa-mir-3925-5p ; hsa-mir-3123 ; hsa-mir-450a-2-3p ; hsa-mir-6083 ; hsa-mir-6857-5p ; hsa-mir-6763-5p ; hsa-mir-6810-5p ; hsa-mir-3150a-3p ; hsa-mir-2110 ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-3147 ; hsa-mir-4425 ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-4705 ; hsa-mir-3200-5p ; hsa-mir-1264 ; hsa-mir-7848-3p ; hsa-mir-6892-3p ; hsa-mir-545-5p ; hsa-mir-624-5p ; hsa-mir-4311

Nearest miRNA

hsa-mir-3690-1/Upstream/125461; hsa-let-7f-2/Downstream/853567;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/124951, chrX-CpG: 49/Downstream/653638

Downstream sequence

CAAGTCATAGGACTGAAAA

Junction sequence