Basic Information
VIS ID
TVIS10006452
Fusion event
HBV-chr7 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1785
Integrated sequence
CGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCC| |AGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCG
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
End
151906852 (Hg38)
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-10399/Upstream/473213; hsa-mir-153-2/Downstream/5667484;
Nearby gene
PRKAG2-AS1(-27629) ; GALNTL5(+49526) ;
Downstream sequence
GGCCATTTTCACAATATA
Junction sequence
GGTCTTTGTACTAGGAGGCTGGCCATTTTCACAATATA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate