Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006460
Fusion event
HBV-HDHD3 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1823
Integrated sequence
AGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTA| |TATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCG
Host Sequence
Chromosome
chr9
Cytoband
q32
Reference genome
Start
End
113373775 (Hg38)
Location type
Exon
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7a-1/Upstream/1441606; hsa-mir-12126/Downstream/835659;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/23866, chr9-CpG: 58/Downstream/2899
Downstream sequence
AATTATCCCCAACATGG
Junction sequence
CGCACCAGCACCATGCAACTAATTATCCCCAACATGG
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.