Basic Information
VIS ID
TVIS10006464
Fusion event
HBV-chr7 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1801
Integrated sequence
AGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCC| |TAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCT
Host Sequence
Chromosome
chr7
Cytoband
q21.11
Reference genome
GRCh38
Start
84597817 (Hg38)
End
84597817 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10525/Upstream/8682548; hsa-mir-10399/Downstream/7606198;
Nearest TSS
ENST00000635602/Upstream/48611; ENST00000422448/Downstream/342428;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/847980, chr7-CpG: 31/Downstream/342105
Nearby gene
LOC101927378(-13499) ; SEMA3D(+397738) ;
Downstream sequence
ACTATTCACAATAGCAAAAG
Junction sequence
GCTGTAGGCATAAATTGGTCACTATTCACAATAGCAAAAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate