VISDB Viral Integration Site DataBase

VIS ID

TVIS10006467

Fusion event

HBV-SEPTIN9 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1829

Integrated sequence

GTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTG| |CGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGAG

Chromosome

chr17

Cytoband

q25.3

Reference genome

Start

End

77440729 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-186-5p ; hsa-mir-10a-5p ; hsa-mir-5587-5p ; hsa-mir-670-5p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-4308 ; hsa-mir-216b-3p ; hsa-mir-4802-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-6500-3p ; hsa-mir-4717-3p ; hsa-mir-3614-5p ; hsa-mir-128-1-5p ; hsa-mir-128-2-5p ; hsa-mir-1914-3p ; hsa-mir-3144-5p ; hsa-mir-3184-5p ; hsa-mir-3191-3p ; hsa-mir-3677-3p ; hsa-mir-423-5p ; hsa-mir-4652-5p ; hsa-mir-4655-3p ; hsa-mir-4710 ; hsa-mir-491-5p ; hsa-mir-5194 ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6781-5p ; hsa-mir-6795-3p ; hsa-mir-6804-5p ; hsa-mir-6810-5p ; hsa-mir-6826-3p ; hsa-mir-6882-3p ; hsa-mir-6887-3p

Nearest miRNA

hsa-mir-10226/Upstream/43675; hsa-mir-1250/Downstream/2266447;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/38284, chr17-CpG: 35/Downstream/10666

Nearest cancer related gene

SEPTIN9(OG, No orient, 0)

Upstream sequence

GTCTGCACAGGTGCCATC

Junction sequence