VISDB Viral Integration Site DataBase

VIS ID

TVIS10006472

Fusion event

HBV-GNAI2 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1822

Integrated sequence

AAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGT| |ATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATC

Chromosome

chr3

Cytoband

p21.31

Reference genome

Start

End

50252682 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-30d-5p ; hsa-mir-30a-5p ; hsa-mir-138-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-935 ; hsa-mir-877-3p ; hsa-mir-92b-3p ; hsa-mir-148b-3p ; hsa-mir-30e-5p ; hsa-mir-30c-5p ; hsa-mir-218-5p ; hsa-mir-30b-5p ; hsa-mir-4328 ; hsa-mir-6516-5p ; hsa-mir-583 ; hsa-mir-3150b-3p ; hsa-mir-4784 ; hsa-mir-625-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-6787-5p ; hsa-mir-6090 ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-8072 ; hsa-mir-3960 ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-3937 ; hsa-mir-455-3p ; hsa-mir-222-3p ; hsa-mir-1237-5p ; hsa-mir-2467-3p ; hsa-mir-3126-5p ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-3196 ; hsa-mir-4488 ; hsa-mir-4530 ; hsa-mir-4697-5p ; hsa-mir-6772-5p ; hsa-mir-6816-5p ; hsa-mir-6873-5p ; hsa-mir-6875-5p ; hsa-mir-922 ; hsa-mir-92b-5p

Nearest miRNA

hsa-mir-12127/Upstream/25192; hsa-let-7g/Downstream/20554;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/14469, chr3-CpG: 67/Downstream/7326

Nearest cancer related gene

GNAI2(OG, No orient, 0)

Upstream sequence

AGGACCAGCCTGGCCAACTTG

Junction sequence