VISDB Viral Integration Site DataBase

VIS ID

TVIS10006473

Fusion event

HBV-ZNF423 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1824

Integrated sequence

GGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTAT| |ATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGG

Chromosome

chr16

Cytoband

q12.1

Reference genome

Start

End

49649494 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-17-3p ; hsa-mir-135b-3p ; hsa-mir-140-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-6783-5p ; hsa-mir-6824-5p ; hsa-mir-873-5p

Nearest miRNA

hsa-mir-1225/Upstream/15485821; hsa-mir-11401/Downstream/643122;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/10680, chr16-CpG: 28/Downstream/48943

Upstream sequence

TCAGCACATATTTAGGAT

Junction sequence