Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006474
Fusion event
HBV-AGBL4 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1737
Integrated sequence
GAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAG| |GATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAG
Host Sequence
Chromosome
chr1
Cytoband
p33
Reference genome
Start
End
49161242 (Hg38)
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-12136/Upstream/4615690; hsa-mir-101-1/Downstream/1898595;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/262001, chr1-CpG: 34/Downstream/862503
Downstream sequence
TCTGGAGCCGAGTACATGGTTCC
Junction sequence
TGTTTGTTTAAAGACTGGGATCTGGAGCCGAGTACATGGTTCC
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.