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VISDB
Viral Integration Site DataBase
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TVIS10006477
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006477
Fusion event
HBV-SNU13 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1828
Integrated sequence
CGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTT| |GCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGA
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh38
Start
41681252 (Hg38)
End
41681252 (Hg38)
Location type
Intron
Fragile sites / regions
FRA22A
Target gene
SNU13
miRNAs that regulate target gene
hsa-mir-23b-3p
;
hsa-mir-92a-3p
;
hsa-mir-5010-5p
;
hsa-mir-6124
;
hsa-mir-4525
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-6797-5p
;
hsa-mir-1249-5p
;
hsa-mir-766-5p
;
hsa-mir-3202
;
hsa-mir-2467-3p
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6127
;
hsa-mir-6129
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-3179
;
hsa-mir-6794-5p
;
hsa-mir-4716-3p
;
hsa-mir-6876-5p
;
hsa-mir-4476
;
hsa-mir-6873-5p
;
hsa-mir-197-3p
;
hsa-mir-4733-3p
;
hsa-mir-1226-3p
;
hsa-mir-5588-3p
;
hsa-mir-6507-3p
Nearest miRNA
hsa-mir-1281/Upstream/428202; hsa-let-7a-3/Downstream/219692;
Nearest TSS
ENST00000624155/Upstream/24299;
ENST00000472110/Downstream/1204;
Nearest CpG islands
None/Target,
chr22-CpG: 279/Upstream/14254
,
chr22-CpG: 42/Downstream/804
Upstream sequence
TCAAAATTTATTTTTGTTCTTA
Junction sequence
TCAAAATTTATTTTTGTTCTTAGAAAAAGTTGCATGGTGCTG
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
7
Sample type
Tumor
Age
28
Gender
Female
CpG Island Information
×
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