VISDB Viral Integration Site DataBase

VIS ID

TVIS10006478

Fusion event

HBV-KLF3 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1807

Integrated sequence

CCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAG| |CCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGT

Chromosome

chr4

Cytoband

p14

Reference genome

Start

End

38669922 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-23a-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-338-5p ; hsa-mir-20b-5p ; hsa-mir-520e ; hsa-mir-520a-3p ; hsa-mir-526b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-519d-3p ; hsa-mir-520d-3p ; hsa-mir-449c-3p ; hsa-mir-302e ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-218-2-3p ; hsa-mir-758-5p ; hsa-mir-6516-5p ; hsa-mir-3658 ; hsa-mir-4639-5p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-6792-5p ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-4708-5p ; hsa-mir-299-5p ; hsa-mir-8086 ; hsa-mir-6870-3p

Nearest miRNA

hsa-mir-12113/Upstream/1427931; hsa-mir-1243/Downstream/198110;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/5012, chr4-CpG: 21/Downstream/18765

Downstream sequence

AAGATGTCCTCTTAA

Junction sequence