VISDB Viral Integration Site DataBase

VIS ID

TVIS10006483

Fusion event

HBV-EPB41 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1791

Integrated sequence

AGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGG| |CAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAA

Chromosome

chr1

Cytoband

p35.3

Reference genome

Start

End

28945637 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-148b-3p ; hsa-mir-320b ; hsa-mir-877-3p ; hsa-mir-423-5p ; hsa-mir-342-3p ; hsa-mir-320a ; hsa-mir-875-3p ; hsa-mir-7703 ; hsa-mir-196a-3p ; hsa-mir-4252 ; hsa-mir-4537 ; hsa-mir-6774-5p ; hsa-mir-635 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-1292-3p ; hsa-mir-4267 ; hsa-mir-1273g-3p ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-508-5p ; hsa-mir-6821-5p ; hsa-mir-4665-3p ; hsa-mir-1268b ; hsa-mir-1268a ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-1908-3p ; hsa-mir-1228-3p ; hsa-mir-6720-5p ; hsa-mir-3685 ; hsa-mir-6079 ; hsa-mir-1299 ; hsa-mir-155-3p ; hsa-mir-671-5p ; hsa-mir-6828-5p ; hsa-mir-6128 ; hsa-mir-1236-3p ; hsa-mir-140-3p ; hsa-mir-6779-3p ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-5001-3p ; hsa-mir-4727-5p ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p

Nearest miRNA

hsa-mir-12136/Upstream/2391044; hsa-mir-101-1/Downstream/1793519;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/30180, chr1-CpG: 384/Downstream/175550

Nearest cancer related gene

EPB41(TSG, No orient, 0)

Upstream sequence

AGTGTTTAATATTCTGTT

Junction sequence