Basic Information
VIS ID
TVIS10006484
Fusion event
HBV-chrX integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1811
Integrated sequence
GCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCAT| |GGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCG
Host Sequence
Chromosome
chrX
Cytoband
p21.3
Reference genome
GRCh38
Start
25732927 (Hg38)
End
25732927 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-23c/Upstream/5715740; hsa-let-7f-2/Downstream/2762628;
Nearest TSS
ENST00000429181/Upstream/716507; ENST00000423914/Downstream/145412;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/709682, chrX-CpG: 30/Downstream/824714
Nearby gene
ARX(-716979) ; MAGEB18(+405415) ;
Upstream sequence
AAACCATAATATACTTCCT
Junction sequence
AAACCATAATATACTTCCTCTGGTGCGCAGACCAATTTA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate