VISDB Viral Integration Site DataBase

VIS ID

TVIS10006486

Fusion event

HBV-EMP2 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1798

Integrated sequence

GAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACA| |GCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCG

Chromosome

chr16

Cytoband

p13.13

Reference genome

Start

End

10557512 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-3165 ; hsa-mir-6880-5p ; hsa-mir-8071 ; hsa-mir-4790-3p ; hsa-mir-6079 ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-3202 ; hsa-mir-4533 ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-5693 ; hsa-mir-383-3p ; hsa-mir-3149 ; hsa-mir-767-5p ; hsa-mir-502-3p ; hsa-mir-501-3p ; hsa-mir-7850-5p ; hsa-mir-5004-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-548aw ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-1290 ; hsa-mir-876-5p ; hsa-mir-3167 ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-8070 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-640 ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-378a-5p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-6759-3p ; hsa-mir-4680-5p ; hsa-mir-4635 ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-4531 ; hsa-mir-4684-5p ; hsa-mir-5703 ; hsa-mir-4434 ; hsa-mir-4516 ; hsa-mir-3675-3p ; hsa-mir-4802-3p ; hsa-mir-6771-3p ; hsa-mir-548c-3p ; hsa-mir-129-5p ; hsa-mir-3119 ; hsa-mir-651-3p

Nearest miRNA

hsa-mir-1225/Upstream/4924946; hsa-mir-11401/Downstream/748928;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/171115, chr16-CpG: 86/Downstream/22511

Nearest cancer related gene

EMP2(TSG, No orient, 0)

Downstream sequence

AAAGTTTTTCCTTGG

Junction sequence