Basic Information
VIS ID
TVIS10006489
Fusion event
HBV-CD99P1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1802
Integrated sequence
GAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCT| |AGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTA
Host Sequence
Chromosome
chrX
Cytoband
p22.33
Reference genome
GRCh38
Start
2621766 (Hg38)
End
2621766 (Hg38)
Location type
Intron
Target gene
CD99P1
Nearest miRNA
hsa-mir-3690-1/Upstream/12512; hsa-let-7f-2/Downstream/3762140;
Nearest TSS
ENST00000429181/Upstream/6419; ENST00000381180/Downstream/69367;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/12110, chrX-CpG: 107/Downstream/69163
Downstream sequence
TTATTGATTACTCATGTAC
Junction sequence
CTGTAGGCATAAATTGGTCTTTATTGATTACTCATGTAC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate