VISDB Viral Integration Site DataBase

VIS ID

TVIS10006495

Fusion event

HBV-TGFBRAP1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1720

Integrated sequence

GAGAAGGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCG| |AGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGAT

Chromosome

chr2

Cytoband

q12.2

Reference genome

Start

End

105319156 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-122-5p ; hsa-mir-628-3p ; hsa-mir-92a-3p ; hsa-mir-181a-5p ; hsa-mir-218-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-5696 ; hsa-mir-4729 ; hsa-mir-4428 ; hsa-mir-6862-5p ; hsa-mir-4253 ; hsa-mir-3945 ; hsa-mir-4711-5p ; hsa-mir-7112-3p ; hsa-mir-6501-3p ; hsa-mir-892c-5p ; hsa-mir-2681-3p ; hsa-mir-181c-5p

Nearest miRNA

hsa-mir-1285-2/Upstream/2886790; hsa-mir-10b/Downstream/3822334;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/49485, chr2-CpG: 62/Downstream/10621

Upstream sequence

AAAAATAAAAAAATCAACAC

Junction sequence