Basic Information
VIS ID
TVIS10006497
Fusion event
HBV-chr11 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1798
Integrated sequence
GAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACA| |GCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCG
Host Sequence
Chromosome
chr11
Cytoband
q22.1
Reference genome
GRCh38
Start
97872304 (Hg38)
End
97872304 (Hg38)
Nearest miRNA
hsa-mir-10392/Upstream/1530778; hsa-let-7a-2/Downstream/3647516;
Nearest TSS
ENST00000527297/Upstream/612317; ENST00000532109/Downstream/70458;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1481881, chr11-CpG: 34/Downstream/1148509
Nearby gene
LINC02713(+6265) ;
Upstream sequence
GCTGGCTGAGCCCAGCA
Junction sequence
GCTGGCTGAGCCCAGCACAATTTATGCCTNCANCCTN
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate