VISDB Viral Integration Site DataBase

VIS ID

TVIS10006505

Fusion event

HBV-KCNK3 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1705

Integrated sequence

CACGGTCCGGCAGATGAGAAGGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAG| |TCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGC

Chromosome

chr2

Cytoband

p23.3

Reference genome

Start

End

26707285 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6825-5p ; hsa-mir-6785-5p ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-8085 ; hsa-mir-149-3p ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-4707-5p ; hsa-mir-6732-5p ; hsa-mir-4296 ; hsa-mir-4322 ; hsa-mir-4265 ; hsa-mir-4417 ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-3656 ; hsa-mir-3621 ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6778-3p ; hsa-mir-150-5p ; hsa-mir-6814-5p ; hsa-mir-3691-3p

Nearest miRNA

hsa-mir-1301/Upstream/1378564; hsa-mir-10b/Downstream/1289082;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/13602, chr2-CpG: 92/Downstream/20385

Upstream sequence

CCCTGGAATGGAGTGCG

Junction sequence