hsa-mir-4646-5p _LIHC.png
hsa-mir-6826-3p _LIHC.png
hsa-mir-187-5p _LIHC.png
hsa-mir-3202 _LIHC.png
hsa-mir-1304-5p _LIHC.png
FBXL18 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006507
Fusion event
HBV-FBXL18 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1813
Integrated sequence
GACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGG| |AAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCA
Host Sequence
Chromosome
chr7
Cytoband
p22.1
Reference genome
End
5495114 (Hg38)
Location type
Intron
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-16-5p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-4709-3p ; hsa-mir-4646-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-4725-3p ; hsa-mir-6780b-5p ; hsa-mir-4271 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6077 ; hsa-mir-6134 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-6783-5p ; hsa-mir-653-5p ; hsa-mir-5585-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-mir-595 ; hsa-mir-8064 ; hsa-mir-6841-3p ; hsa-mir-5587-3p ; hsa-mir-6840-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3679-3p ; hsa-mir-6749-3p ; hsa-mir-6826-3p ; hsa-mir-5193 ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-6887-3p ; hsa-mir-6795-3p ; hsa-mir-5089-3p ; hsa-mir-4703-3p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-139-5p ; hsa-mir-7852-3p ; hsa-mir-513b-3p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-1205 ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-1909-3p ; hsa-mir-195-5p ; hsa-mir-3064-3p ; hsa-mir-3121-3p ; hsa-mir-3151-5p ; hsa-mir-3160-3p ; hsa-mir-3179 ; hsa-mir-3202 ; hsa-mir-342-5p ; hsa-mir-3918 ; hsa-mir-3919 ; hsa-mir-424-5p ; hsa-mir-4313 ; hsa-mir-4319 ; hsa-mir-4433a-3p ; hsa-mir-4447 ; hsa-mir-4459 ; hsa-mir-4472 ; hsa-mir-4487 ; hsa-mir-4497 ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-4651 ; hsa-mir-4664-5p ; hsa-mir-4695-5p ; hsa-mir-4747-5p ; hsa-mir-4756-3p ; hsa-mir-4768-3p ; hsa-mir-4792 ; hsa-mir-491-5p ; hsa-mir-497-5p ; hsa-mir-503-5p ; hsa-mir-5196-5p ; hsa-mir-544b ; hsa-mir-558 ; hsa-mir-608 ; hsa-mir-646 ; hsa-mir-6717-5p ; hsa-mir-6722-3p ; hsa-mir-6732-5p ; hsa-mir-6737-5p ; hsa-mir-6742-5p ; hsa-mir-6747-5p ; hsa-mir-6758-5p ; hsa-mir-6781-5p ; hsa-mir-6796-5p ; hsa-mir-6804-5p ; hsa-mir-6812-5p ; hsa-mir-6819-5p ; hsa-mir-6829-5p ; hsa-mir-6838-5p ; hsa-mir-6846-3p ; hsa-mir-6856-5p ; hsa-mir-129-5p ; hsa-mir-1304-5p ; hsa-mir-25-5p ; hsa-mir-3197 ; hsa-mir-6087 ; hsa-mir-6765-5p ; hsa-mir-8055 ; hsa-mir-4294
Nearest miRNA
hsa-mir-339/Upstream/706475; hsa-mir-10399/Downstream/705;
Nearest CpG islands
chr7-CpG: 28/Target, None/Upstream, None/Downstream
Downstream sequence
AGGAAAAGGCTCCCACTGC
Junction sequence
AATTGGTGTGTTCACCAGCAAGGAAAAGGCTCCCACTGC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate