Basic Information
VIS ID
TVIS10006514
Fusion event
HBV-chrX integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chrX
Cytoband
q22.2
Reference genome
GRCh38
Start
103653329 (Hg38)
End
103653329 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/8590103; hsa-mir-105-1/Downstream/2986485;
Nearest TSS
ENST00000429181/Upstream/24330; ENST00000435306/Downstream/23602;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/23580, chrX-CpG: 38/Downstream/33850
Nearby gene
TCEAL1(-22381) ; MORF4L2(+22168) ;
Upstream sequence
cctcaatttggtcgggtgtctgagccccacctctggagtcaagtcctgcctactacttcattcccccctcaaacagtagatattcatccttaatcttaat
Downstream sequence
ggggctgcagaagggcagaagtccatcttctgtaactgcttcctgctgagtttatgggagtaggcagtgcctagcaccagatgactaaaaaatctctgga
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate