NRG3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006518
Fusion event
HBV-NRG3 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1743
Integrated sequence
GCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCA| |GCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAAC
Host Sequence
Chromosome
chr10
Cytoband
q23.1
Reference genome
GRCh38
Start
82316697 (Hg38)
End
82316697 (Hg38)
Location type
Intron
Fragile sites / regions
FRA10D
Target gene
NRG3
Nearest miRNA
hsa-mir-1265/Upstream/6764144; hsa-mir-107/Downstream/3947997;
Nearest TSS
ENST00000439456/Upstream/87518; ENST00000537893/Downstream/421879;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/440724, chr10-CpG: 24/Downstream/1248246
Downstream sequence
TCTACTTCTAAAAAGGA
Junction sequence
GTGTTTACTGAGTGGGAGGATCTACTTCTAAAAAGGA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate