Basic Information
VIS ID
TVIS10006520
Fusion event
HBV-LINC01483 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1819
Integrated sequence
GAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGA| |TGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGG
Host Sequence
Chromosome
chr17
Cytoband
q24.3
Reference genome
GRCh38
Start
69641717 (Hg38)
End
69641717 (Hg38)
Location type
Intron
Target gene
LINC01483
Nearest miRNA
hsa-mir-10226/Upstream/542061; hsa-mir-1250/Downstream/5106896;
Nearest TSS
ENST00000595228/Upstream/46851; ENST00000587241/Downstream/121960;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/314021, chr17-CpG: 87/Downstream/527055
Upstream sequence
TTTGTTTAAGGGGAA
Junction sequence
TTTGTTTAAGGGGAAGCATGGTGCTGGTGAACACA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate