Basic Information
VIS ID
TVIS10006522
Fusion event
HBV-chr8 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh38
Start
55581800 (Hg38)
End
55581800 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/12685525; hsa-mir-10400/Downstream/6132988;
Nearest TSS
ENST00000518652/Upstream/55614; ENST00000519494/Downstream/164247;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/132192, chr8-CpG: 77/Downstream/191133
Nearby gene
XKR4(-55649) ; TMEM68(+156943) ;
Upstream sequence
TACAAACCAGGGTAATAACTTTCTTTCCAAAAAATTCTGCTTGCTTAATTGCCAAGAAACATGATAGGCAATAGGCTTTGGTTGATTTAAAATAGTGGTT
Downstream sequence
TCCTTTCTTTTCTTCCCCCATCAGGAACTTTTGTTCAAACAAATTCTATTCAAATGCCAAAAGCCTCCTTCCAGTGCCTGCCCGGCATCCACCTCTCCTC
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate