VISDB Viral Integration Site DataBase

VIS ID

TVIS10006525

Fusion event

HBV-EPS15L1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1690

Integrated sequence

GTGAAGCGAAGTGCACACGGTCCGGCAGATGAGAAGGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAG| |AAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTG

Chromosome

chr19

Cytoband

p13.11

Reference genome

Start

End

16397387 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-885-3p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-6804-5p ; hsa-mir-185-5p ; hsa-mir-558 ; hsa-mir-1233-3p ; hsa-mir-3192-5p ; hsa-mir-5739 ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-6779-3p ; hsa-mir-3678-3p ; hsa-mir-2467-3p ; hsa-mir-6801-5p ; hsa-mir-4257 ; hsa-mir-759 ; hsa-mir-329-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4803 ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-3609 ; hsa-mir-548ah-5p

Nearest miRNA

hsa-mir-10395/Upstream/947779; hsa-let-7e/Downstream/1884690;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/41561, chr19-CpG: 22/Downstream/20560

Downstream sequence

GCTGTTTGTCTATTTTAC

Junction sequence