Basic Information
VIS ID
TVIS10006528
Fusion event
HBV-chr5 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1828
Integrated sequence
CGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTT| |GCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGA
Host Sequence
Chromosome
chr5
Cytoband
p15.31
Reference genome
End
7013040 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-4277/Upstream/185119; hsa-mir-10397/Downstream/1447885;
Nearby gene
MIR4278(-185119) ; MIR4454(+256262) ;
Downstream sequence
CTTGATGATTAGTCAT
Junction sequence
CAGCACCATGCAACTTTTTCCTTGATGATTAGTCAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate