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VISDB
Viral Integration Site DataBase
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TVIS10006530
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006530
Fusion event
HBV-BPNT1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1819
Integrated sequence
GAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGA| |TGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGG
Host Sequence
Chromosome
chr1
Cytoband
q41
Reference genome
GRCh38
Start
220059053 (Hg38)
End
220059053 (Hg38)
Location type
Intron
Target gene
BPNT1
miRNAs that regulate target gene
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-7977
;
hsa-mir-1289
;
hsa-mir-1827
;
hsa-mir-383-3p
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6071
;
hsa-mir-6828-3p
;
hsa-mir-5001-3p
;
hsa-mir-4497
;
hsa-mir-4437
;
hsa-mir-5581-5p
;
hsa-mir-4297
;
hsa-mir-3182
;
hsa-mir-4772-3p
;
hsa-mir-1304-3p
;
hsa-mir-6890-3p
;
hsa-mir-335-5p
;
hsa-mir-665
;
hsa-mir-6894-3p
;
hsa-mir-455-3p
;
hsa-mir-6771-5p
;
hsa-mir-550a-5p
;
hsa-mir-550a-3-5p
;
hsa-mir-1271-3p
;
hsa-mir-3622b-5p
;
hsa-mir-7160-5p
;
hsa-mir-4746-3p
;
hsa-mir-4763-5p
;
hsa-mir-4722-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-17-3p
;
hsa-mir-4649-3p
;
hsa-mir-6746-5p
;
hsa-mir-1247-3p
;
hsa-mir-4768-3p
;
hsa-mir-5690
;
hsa-mir-5588-3p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-5197-5p
;
hsa-mir-25-5p
;
hsa-mir-4327
;
hsa-mir-4537
;
hsa-mir-6087
;
hsa-mir-6499-3p
;
hsa-mir-6516-5p
Nearest miRNA
hsa-mir-101-1/Upstream/7981368; hsa-mir-1182/Downstream/58800;
Nearest TSS
ENST00000473358/Upstream/12395;
ENST00000490891/Downstream/15014;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/12334
,
chr1-CpG: 63/Downstream/34919
Upstream sequence
TGGATTGTGGTTTTTCTAG
Junction sequence
TGGATTGTGGTTTTTCTAGAGCATGGTGCTGGTGCGCAGA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
10
Sample type
Tumor
Age
14
Gender
Female
CpG Island Information
×
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