Basic Information
VIS ID
TVIS10006541
Fusion event
HBV-chr15 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1808
Integrated sequence
CAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGC| |CATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTT
Host Sequence
Chromosome
chr15
Cytoband
q25.2
Reference genome
GRCh38
Start
82533803 (Hg38)
End
82533803 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10393/Upstream/1536330; hsa-mir-11181/Downstream/533532;
Nearest TSS
ENST00000557528/Upstream/103758; ENST00000621893/Downstream/6328;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/19709, chr15-CpG: 95/Downstream/6081
Nearby gene
GOLGA6L17P(-7319) ; RPS17(+2946) ;
Downstream sequence
TCAAGCGATCCTCCTGCCT
Junction sequence
GCATAAATTGGTCTGCGCACTCAAGCGATCCTCCTGCCT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate