Basic Information
VIS ID
TVIS10006543
Fusion event
HBV-ZMIZ1-AS1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr10
Cytoband
q22.3
Reference genome
GRCh38
Start
79033393 (Hg38)
End
79033393 (Hg38)
Location type
Intron
Fragile sites / regions
FRA10D
Target gene
ZMIZ1-AS1
Nearest miRNA
hsa-mir-1265/Upstream/3480840; hsa-mir-107/Downstream/7231301;
Nearest TSS
ENST00000439456/Upstream/29590; ENST00000472035/Downstream/34075;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/59137, chr10-CpG: 270/Downstream/33614
Downstream sequence
ACCGGTTTACATCATTCA
Junction sequence
CGCACCAGCACCATGCAACTCTACCGGTTTACATCATTCA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate