VISDB Viral Integration Site DataBase

VIS ID

TVIS10006544

Fusion event

HBV-IRAK1BP1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1828

Integrated sequence

CGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTT| |GCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGA

Chromosome

chr6

Cytoband

q14.1

Reference genome

Start

End

78898764 (Hg38)

Location type

Exon

Target gene

miRNAs that regulate target gene

hsa-mir-759 ; hsa-mir-892c-5p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-7703 ; hsa-mir-25-5p ; hsa-mir-196a-3p ; hsa-mir-658 ; hsa-mir-661 ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-4537 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-508-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-451b ; hsa-mir-6501-3p ; hsa-mir-6512-3p ; hsa-mir-6720-5p

Nearest miRNA

hsa-mir-10398/Upstream/359455; hsa-mir-1202/Downstream/11413978;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/30725, chr6-CpG: 44/Downstream/11849

Downstream sequence

TTGTAAGACAAAATTT

Junction sequence