MYT1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006545
Fusion event
HBV-MYT1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1828
Integrated sequence
CGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTT| |GCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGA
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh38
Start
64198457 (Hg38)
End
64198457 (Hg38)
Location type
Intron
Target gene
MYT1
miRNAs that regulate target gene
hsa-mir-27a-3p
Nearest miRNA
hsa-mir-1-1/Upstream/121447;
Nearest TSS
ENST00000382410/Upstream/33845; ENST00000609297/Downstream/57238;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/10918, chr20-CpG: 85/Downstream/56878
Upstream sequence
CCTGATGCCT CAGCACCTGC
Junction sequence
CCTGATGCCTCAGCACCTGCGGAAAAAGTTGCATGGNGCTG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate