Basic Information
VIS ID
TVIS10006547
Fusion event
HBV-chr8 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1793
Integrated sequence
GGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCA| |GCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAAC
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh38
Start
59680145 (Hg38)
End
59680145 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/16783870; hsa-mir-10400/Downstream/2034643;
Nearest TSS
ENST00000518652/Upstream/78741; ENST00000531077/Downstream/369442;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/559958, chr8-CpG: 14/Downstream/493421
Nearby gene
TOX(-560937) ; CA8(+508718) ;
Upstream sequence
CTCCAGCATTTTGAGTA
Junction sequence
CTCCAGCATTTTGAGTATATGCCTACAGCCTCCTAAT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate