VISDB Viral Integration Site DataBase

VIS ID

TVIS10006550

Fusion event

HBV-GRAMD4 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1783

Integrated sequence

GACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGAT| |CCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTG

Chromosome

chr22

Cytoband

q13.31

Reference genome

Start

End

46582920 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-32-5p ; hsa-mir-149-5p ; hsa-mir-665 ; hsa-mir-944 ; hsa-mir-548f-5p ; hsa-mir-548g-5p ; hsa-mir-548x-5p ; hsa-mir-548aj-5p ; hsa-mir-4768-3p ; hsa-mir-548aw ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-505-3p ; hsa-mir-2467-3p ; hsa-mir-1468-3p ; hsa-mir-140-3p ; hsa-mir-4257 ; hsa-mir-137 ; hsa-mir-367-3p ; hsa-mir-25-3p ; hsa-mir-363-3p ; hsa-mir-92a-3p ; hsa-mir-92b-3p

Nearest miRNA

hsa-let-7a-3/Upstream/469152; hsa-mir-12114/Downstream/1691444;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/5208, chr22-CpG: 28/Downstream/35471

Nearby gene

CELSR1(-45750) ; GRAMD4(+43840) ;

Downstream sequence

CTTTCTCTCTCTTTTGTCT

Junction sequence