Basic Information
VIS ID
TVIS10006552
Fusion event
HBV-chr14 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr14
Cytoband
q13.1
Reference genome
GRCh38
Start
34499424 (Hg38)
End
34499424 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/3484682; hsa-mir-1185-1/Downstream/2452885;
Nearest TSS
ENST00000550708/Upstream/36650; ENST00000554608/Downstream/37021;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/36801, chr14-CpG: 43/Downstream/39896
Nearby gene
SPTSSA(-37162) ; EAPP(+16504) ;
Upstream sequence
aggctggagtgcagtggcgtgatctcagctcaatgcaacctccgcctcccgggttcaagtgattctcctgcctcagcctcctgagtaggtgggattagag
Downstream sequence
gcgcctgccaccacgcctgactaatttttttttctttttttttttgagctagagtctgactctgtcgcccaggctggagtgaagtgcagcaggctggtct
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate