Basic Information
VIS ID
TVIS10006554
Fusion event
HBV-chr20 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1671
Integrated sequence
CTCCATGCGACGTGCAGAGGTGAAGCGAAGTGCACACGGTCCGGCAGATGAGAAGGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCG| |GTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGT
Host Sequence
Chromosome
chr20
Cytoband
q11.21
Reference genome
GRCh38
Start
30421656 (Hg38)
End
30421656 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/4213378; hsa-mir-1-1/Downstream/1185530;
Nearest TSS
ENST00000382410/Upstream/59926; ENST00000400552/Downstream/836008;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/43975, chr20-CpG: 38/Downstream/62468
Nearby gene
MLLT10P1(-18194) ; DEFB115(+836007) ;
Upstream sequence
TGCATATGGAATGTCTG
Junction sequence
TGCATATGGAATGTCTGCCAAGAGTCCTCTTA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate