Basic Information
VIS ID
TVIS10006557
Fusion event
HBV-chr9 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr9
Cytoband
p21.3
Reference genome
GRCh38
Start
24112457 (Hg38)
End
24112457 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA9C
Nearest miRNA
hsa-mir-101-2/Upstream/2600272; hsa-let-7a-1/Downstream/4751169;
Nearest TSS
ENST00000422679/Upstream/214403; ENST00000602614/Downstream/433219;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/260933, chr9-CpG: 111/Downstream/1565039
Nearby gene
ELAVL2(-286392) ; IZUMO3(+430757) ;
Downstream sequence
AGTGATTCTCCTGCCTCA
Junction sequence
AGTGATTCTCCTGCCTCA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate