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VISDB
Viral Integration Site DataBase
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TVIS10006559
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006559
Fusion event
HBV-SHISA9 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1791
Integrated sequence
AGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGG| |CAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAA
Host Sequence
Chromosome
chr16
Cytoband
p13.12
Reference genome
GRCh38
Start
13012870 (Hg38)
End
13012870 (Hg38)
Location type
Intron
Target gene
SHISA9
miRNAs that regulate target gene
hsa-mir-4531
;
hsa-mir-7847-3p
;
hsa-mir-4764-5p
;
hsa-mir-5192
;
hsa-mir-4644
;
hsa-mir-4306
;
hsa-mir-185-5p
;
hsa-mir-5703
;
hsa-mir-4516
;
hsa-mir-4434
;
hsa-mir-1287-5p
;
hsa-mir-3135b
;
hsa-mir-3605-5p
;
hsa-mir-764
;
hsa-mir-4657
;
hsa-mir-4491
;
hsa-mir-1265
;
hsa-mir-3914
;
hsa-mir-5096
;
hsa-mir-7641
;
hsa-mir-197-3p
;
hsa-mir-4695-3p
;
hsa-mir-4716-5p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-1911-3p
;
hsa-mir-4261
;
hsa-mir-873-5p
;
hsa-mir-1285-5p
;
hsa-mir-4496
;
hsa-mir-552-3p
;
hsa-mir-5197-5p
;
hsa-mir-374b-5p
;
hsa-mir-374a-5p
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-369-3p
;
hsa-mir-508-5p
;
hsa-mir-3145-5p
;
hsa-mir-548l
;
hsa-mir-8054
;
hsa-mir-548k
;
hsa-mir-548av-5p
;
hsa-mir-559
;
hsa-mir-548y
;
hsa-mir-548w
;
hsa-mir-548o-5p
;
hsa-mir-548j-5p
;
hsa-mir-548i
;
hsa-mir-548h-5p
;
hsa-mir-548d-5p
;
hsa-mir-548c-5p
;
hsa-mir-548bb-5p
;
hsa-mir-548b-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548au-5p
;
hsa-mir-548as-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548am-5p
;
hsa-mir-548ak
;
hsa-mir-548ae-5p
;
hsa-mir-548ad-5p
;
hsa-mir-548ab
;
hsa-mir-548a-5p
;
hsa-mir-3187-3p
;
hsa-mir-653-3p
;
hsa-mir-4529-5p
;
hsa-mir-6847-3p
;
hsa-mir-539-5p
;
hsa-mir-3190-5p
;
hsa-mir-3919
;
hsa-mir-4756-3p
;
hsa-mir-548o-3p
;
hsa-mir-5680
;
hsa-mir-1323
;
hsa-mir-193b-3p
;
hsa-mir-193a-3p
;
hsa-mir-551b-5p
;
hsa-mir-497-3p
;
hsa-mir-548t-3p
;
hsa-mir-548ap-3p
;
hsa-mir-548aa
;
hsa-mir-7156-3p
;
hsa-mir-6516-3p
;
hsa-mir-1206
;
hsa-mir-1272
;
hsa-mir-3662
;
hsa-mir-8084
;
hsa-mir-642a-5p
;
hsa-mir-6883-3p
;
hsa-mir-6515-3p
;
hsa-mir-6734-3p
;
hsa-mir-877-3p
;
hsa-mir-2276-5p
;
hsa-mir-6892-3p
;
hsa-mir-454-5p
;
hsa-mir-4277
;
hsa-mir-584-3p
;
hsa-mir-6505-5p
;
hsa-mir-4789-5p
;
hsa-mir-7153-3p
;
hsa-mir-129-5p
;
hsa-mir-1304-3p
;
hsa-mir-4474-5p
;
hsa-mir-483-3p
;
hsa-mir-8055
Nearest miRNA
hsa-mir-1225/Upstream/292499; hsa-mir-11401/Downstream/1291097;
Nearest TSS
ENST00000527434/Upstream/109991;
ENST00000566106/Downstream/69510;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/109037
,
chr16-CpG: 56/Downstream/907024
Upstream sequence
GTATTAGGAGGCTGTAGGCA
Junction sequence
GTATTAGGAGGCTGTAGGCAAACTTTCAAAAGGGT
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
10
Sample type
Tumor
Age
14
Gender
Female
CpG Island Information
×
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