VISDB Viral Integration Site DataBase

VIS ID

TVIS10006565

Fusion event

HBV-FOXN3 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1910

Integrated sequence

TGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCC| |GCAGTATGGATCGGCAGAGGAGCCGAAAAGGTTCCACGCATGCGCTGATGGCCCATGACCAAGCCCCAGCCAGTGGGGGTTGCGTCAGCAAACACTTGGC

Chromosome

chr14

Cytoband

q31.3

Reference genome

Start

End

89211096 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-574-5p ; hsa-mir-21-5p ; hsa-mir-92b-3p ; hsa-mir-210-3p ; hsa-mir-4777-3p ; hsa-mir-5096 ; hsa-mir-6790-5p ; hsa-mir-4658 ; hsa-mir-197-3p ; hsa-mir-4477a ; hsa-mir-921 ; hsa-mir-1257 ; hsa-mir-6073 ; hsa-mir-548au-3p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-3659 ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-16-1-3p ; hsa-mir-425-5p ; hsa-mir-3174 ; hsa-mir-7153-3p ; hsa-mir-562 ; hsa-mir-6878-3p ; hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-4684-3p ; hsa-mir-203a-3p ; hsa-mir-1245b-3p ; hsa-mir-888-5p ; hsa-mir-409-3p ; hsa-mir-335-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-890 ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-374a-3p ; hsa-mir-3686 ; hsa-mir-3607-3p ; hsa-mir-34c-3p ; hsa-mir-4762-3p ; hsa-mir-3192-3p ; hsa-mir-29a-5p ; hsa-mir-3920 ; hsa-mir-6509-5p ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-370-5p ; hsa-mir-6867-5p

Nearest miRNA

hsa-mir-1260a/Upstream/11944806; hsa-mir-1185-1/Downstream/4737130;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/48241, chr14-CpG: 200/Downstream/205099

Downstream sequence

AGTTTCATTACCTTTCAAC

Junction sequence