Basic Information
VIS ID
TVIS10006566
Fusion event
HBV-chr12 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1797
Integrated sequence
CGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCAC| |AGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGC
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
End
84639238 (Hg38)
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-let-7i/Upstream/3480777; hsa-mir-1178/Downstream/2105830;
Nearby gene
SLC6A15(+220249) ;
Downstream sequence
TAGTTACTTCATAAATGTTGA
Junction sequence
GGAAGGCTGTAGGCATAAATTAGTTACTTCATAAATGTTGA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate