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VISDB
Viral Integration Site DataBase
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TVIS10006566
Basic Information
VIS ID
TVIS10006566
Fusion event
HBV-chr12 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1797
Integrated sequence
CGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCAC| |AGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGC
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
GRCh38
Start
84639238 (Hg38)
End
84639238 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA12B
Nearest miRNA
hsa-let-7i/Upstream/3480777; hsa-mir-1178/Downstream/2105830;
Nearest TSS
ENST00000382841/Upstream/354847;
ENST00000393212/Downstream/228595;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/1951371
,
chr12-CpG: 17/Downstream/272183
Nearby gene
SLC6A15
(+220249) ;
Downstream sequence
TAGTTACTTCATAAATGTTGA
Junction sequence
GGAAGGCTGTAGGCATAAATTAGTTACTTCATAAATGTTGA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
11
Sample type
Tumor
Age
14
Gender
Female
CpG Island Information
×
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