Basic Information
VIS ID
TVIS10006574
Fusion event
HBV-chr8 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1819
Integrated sequence
GAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGA| |TGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGG
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
End
143235361 (Hg38)
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-1204/Upstream/1058943; hsa-mir-10400/Downstream/497722;
Nearby gene
GPIHBP1(-18191) ; ZFP41(+11459) ;
Downstream sequence
GATTACAGGATCACACACA
Junction sequence
TCTGCGCACCAGCNCCATGCTGATTACAGGATCACACACA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate