VISDB Viral Integration Site DataBase

VIS ID

TVIS10006575

Fusion event

HBV-AHI1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1777

Integrated sequence

ACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCG| |CAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGAC

Chromosome

chr6

Cytoband

q23.3

Reference genome

Start

End

135385660 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-148b-3p ; hsa-mir-218-5p ; hsa-mir-619-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6778-3p ; hsa-mir-150-5p ; hsa-mir-6814-5p ; hsa-mir-4761-5p ; hsa-mir-6504-3p ; hsa-mir-3159 ; hsa-mir-4735-3p ; hsa-mir-4438 ; hsa-mir-18b-5p ; hsa-mir-18a-5p ; hsa-mir-331-5p ; hsa-mir-636 ; hsa-mir-3618 ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-1283 ; hsa-mir-455-5p ; hsa-mir-4678 ; hsa-mir-4517

Nearest miRNA

hsa-mir-10398/Upstream/146404; hsa-mir-1202/Downstream/3049553;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/202387, chr6-CpG: 84/Downstream/111703

Nearest cancer related gene

AHI1(OG, No orient, 0)

Upstream sequence

CTATGAAACCTGTGAATT

Junction sequence