Basic Information
VIS ID
TVIS10006580
Fusion event
HBV-chr3 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr3
Cytoband
q12.1
Reference genome
GRCh38
Start
98942382 (Hg38)
End
98942382 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/2582343; hsa-mir-12124/Downstream/1021932;
Nearest TSS
ENST00000440867/Upstream/39958; ENST00000473756/Downstream/38676;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/40330, chr3-CpG: 43/Downstream/875387
Nearby gene
DCBLD2(-41056) ; COL8A1(+696213) ;
Upstream sequence
GAGTAAATTTGTTAATACCACATTTCTCTTTAATTCAGAGATTGAAAGATAAGGTTGCTCAGATCAACAGATATTTATTGACCTATTCTATTCAATTGAT
Downstream sequence
ACTTGAATGTCTAGATTTTAATCGAAATGAATTTCAGAGTTAGAGGATTTTAATAATGATAAAAAAAATCAAGGTGTGTCAGATCTTGCTGATTCCTTCA
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate