Basic Information
VIS ID
TVIS10006581
Fusion event
HBV-chr9 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1794
Integrated sequence
GGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAG| |CACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACA
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh38
Start
98882830 (Hg38)
End
98882830 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7a-1/Upstream/653613; hsa-mir-12126/Downstream/7718098;
Nearest TSS
ENST00000422679/Upstream/10415; ENST00000467052/Downstream/60349;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/74763, chr9-CpG: 75/Downstream/60795
Nearby gene
GALNT12(-32749) ; COL15A1(+60882) ;
Upstream sequence
TTTCTTTCCCCTGTCCTTTC
Junction sequence
TTTCTTTCCCCTGTCCTTTCTTATGCCTNCAGCCTCCTAA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate