Basic Information
VIS ID
TVIS10006585
Fusion event
HBV-LOC105377842 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1729
Integrated sequence
CAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTC| |GTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTG
Host Sequence
Chromosome
chr6
Cytoband
q12
Reference genome
GRCh38
Start
67321866 (Hg38)
End
67321866 (Hg38)
Location type
Intronic
Target gene
LOC105377842
Nearest miRNA
hsa-mir-10398/Upstream/9931654; hsa-mir-10524/Downstream/4055094;
Nearest TSS
ENST00000381078/Upstream/1614641; ENST00000449928/Downstream/567473;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1226928, chr6-CpG: 37/Downstream/1312974
Nearby gene
LOC102723883(+733484) ;
Downstream sequence
AGGTTAGACTTTTTGGTAC
Junction sequence
ACTGTTTGTTTAAGAGGTTAGACTTTTTGGTAC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate